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I have a 7200 with 2 cages: 2 SSD and 11 SAS disks per cage. SSD is for AFC.
You should have an even number of disks per cage, not saying it won't work but it's not a supported configuration, so one cage should have 14 disks and the other 12.
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What about the set size ? What is the best practice ?
22 isn't ideal, 24 would have provided more choices, so you'll have a few chunklets left over, to maintain balance and minimize this I would run either of the following:-
4+1 = 4 x 4+1 =20
8+1 = 2 x 8+1 =20
You'll still access and use all the disks as the set sizes will wrap around. it's just you won't be able to access every last chunklet as eventually 2 disks will have more free and you can't form a 4+1 or 8+1 across only 2 disks. So ideally the set size you choose should divide evenly into the number of disks and the number of sets be evenly divisible by the number of controllers.